Table 3. Toxicity of the FOLFOXIRI/erbitux combination in all patients and all cycles.
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | |||||
|---|---|---|---|---|---|---|---|---|
| No. of patients | % | No. of patients | % | No. of patients | % | No. of patients | % | |
| Haematologic toxicity | ||||||||
| Neutropenia | 3 | 10.0 | 5 | 16.7 | 6 | 20.0 | 1 | 3.3 |
| Anaemia | 13 | 43.3 | 10 | 33.3 | 1 | 3.3 | — | — |
| Thrombocytopenia | 7 | 23.3 | — | — | — | — | 2 | 6.7 |
| Febrile neutropenia | — | — | 1 | 3.3 | — | — | 1 | 3.3 |
| Non-haematologic toxicity | ||||||||
| Nausea | 6 | 20.0 | 3 | 10.0 | 1 | 3.3 | — | — |
| Vomiting | 3 | 10.0 | 3 | 10.0 | 4 | 13.3 | — | — |
| Diarrhoea | 6 | 20.0 | 5 | 16.7 | 13 | 43.3 | 3 | 10.0 |
| Stomatitis | 5 | 16.7 | 5 | 16.7 | 3 | 10.0 | — | — |
| Constipation | 3 | 10.0 | — | — | — | — | — | — |
| Neurotoxicity | 7 | 23.3 | 2 | 6.7 | — | — | — | — |
| Allergy | 5 | 16.7 | 4 | 13.3 | — | — | — | — |
| Asthenia | 8 | 26.7 | 6 | 20.0 | — | — | — | — |
| Hand/Foot | 2 | 6.7 | 3 | 10.0 | 1 | 3.3 | — | — |
| Rush | 6 | 20.0 | 4 | 13.3 | 1 | 3.3 | — | — |