Table 2. Pathological details of the patients.
| S | CS | CRTS | P -value | |
|---|---|---|---|---|
| Number | 103 | 124 | 42 | |
| CPR | NA | 3 (2.5) | 15 (35.7) | <0.0001a |
| pT stage | <0.0001 a | |||
| T1 | 34 (33.0) | 9 (7.3) | 4 (9.5) | |
| T2 | 18 (17.5) | 20 (16.1) | 6 (14.3) | |
| T3 | 50 (48.5) | 88 (71.0) | 15 (35.7) | |
| T4 | 1 (1.0) | 4 (3.2) | 2 (4.8) | |
| pN stage | <0.0001 a | |||
| N0 | 56 (54.4) | 42 (33.9) | 30 (71.4) | |
| N1 | 47 (45.6) | 82 (66.1) | 12 (28.6) | |
| Tumour grade | 0.087 a | |||
| Well | 13 (12.6) | 8 (6.5) | 1 (2.4) | |
| Moderate | 52 (50.5) | 54 (43.5) | 9 (21.4) | |
| Poor | 29 (28.2) | 54 (43.5) | 11 (26.2) | |
| Not reported | 9 (9.4) | 5 (4.0) | 6 (14.3) | |
| CRM | <0.0001 a | |||
| Negative | 67 (65.0) | 57 (46.0) | 36 (85.7) | |
| Positive | 30 (29.1) | 63 (50.9) | 5 (12.0) | |
| Not reported | 6 (5.8) | 4 (3.2) | 1 (2.4) | |
| LV invasion | 0.011 a | |||
| No | 49 (48.0) | 57 (48.0) | 27 (64.3) | |
| Yes | 31 (30.1) | 55 (44.4) | 7 (16.7) | |
| Not reported | 23 (22.3) | 12 (9.7) | 8 (19.0) | |
| LNs | ||||
| Median LNMC | 0 (1–13) | 1 (0–18) | 0 (0–6) | <0.0001b |
| Median LN harvest | 10 (2–41) | 13.5 (1–38) | 10 (0–39) | 0.001b |
Abbreviations: CPR=complete pathological response to neoadjuvant therapy; CRM=circumferential resection margin; CRTS=neoadjuvant chemoradiotherapy; CS=neoadjuvant chemotherapy; LN=lymph node; LNMC=lymph node metastasis count; LV=lymphovascular; NA=not applicable; S=surgery alone.
All figures are numbers (%), with the exception of lymph node counts, which are median (range).
a
χ2 test.
b
Mann–Whitney U-test. Italic values indicate P<0.0001.