Table 1.

Demographic and clinical characteristics of patients with early and late lesions (plaques).

Demographic and clinical characteristics
EL/LL	Age	Sex	BMI	Smoker	DM	Infections	Hypercholesterolemia	CRP	Hypertension	History of CVD	Therapy	Lesion score I–IV
EL1	65	F	36	ND	No	No	No	1.45	Yes	PAE	Antibiotics, anticoagulation, antidiabetic, antihemorrhagic, catecholamine, cardiovascular medication, protone pump inhibitor, thyroidal, ureostatic	II
EL2a	46	M	24	ND	No	Urinary tract infection	Yes	2.67	Yes	No	Antibiotics, anticoagulation, antidiabetic, antidiuretic, cardiovascular medication, protone pump inhibitor, steroid, secretolytic	ND
EL3	48	M	28	Yes	No	No	Yes	9.8	Yes	No	Antibiotics, antidiabetic, cardiovascular medication	II
EL4a,b	55	F	19	No	No	No	Yes	0.5	No	No	Catecholamine	ND
EL5a	70	M	26	No	No	No	ND	31.9	No	No	Antidiuretic	ND
EL6	65	M	25	ND	No	No	ND	1.55	Yes	No	Analgesic, antibiotic, anticoagulation, cardiovascular medication, protone pump inhibitor	II
EL7	29	M	25	No	No	No	No	10.6	No	No	Antibiotic, catecholamines	II
LL1	70	M	29.2	No	Yes	No	Yes	0.07	Yes	No	Anticoagulation, cardiovascular medication, protone pump inhibitor, respiratory tract, steroid	V
LL2	77	M	21	No	No	Candidiasis	Yes	0.06	Yes	CHD, MI, PAOD	Anticoagulation, cardiovascular medication, protone pump inhibitor	V
LL3	82	F	18.2	Nob	No	No	No	0.06	Yes	No	Anticoagulation, cardiovascular medication, neuroleptic medication	V
LL4	72	F	25.5	No	No	No	Yes	0.2	Yes	No	Anticoagulation, cardiovascular medication	V
LL5	85	M	22.6	No	No	No	Yes	0.7	Yes	CHD, PAOD, ACM infarction	Anticoagulation, cardiovascular medication	V
LL6	76	M	20.6	No	No	No	No	0.07	Yes	ACM infarction	Anticoagulation, protone pump inhibitor, ureostatic	V
LL7	56	M	25.5	Yes	No	No	Yesc	0.4	No	CHD, NSTEMI, stroke	Anticoagulation, antidepressivum/antipsychotic/antiepileptic, cardiovascular medication, vitamin	V
LL8	75	M	23.5	No	No	No	Yes	0.15	Yes	CHD, TIA, ACM infarction	Anticoagulation, cardiovascular medication	V

EL = early lesion, LL = late lesion (plaques), F = female, M = male, BMI = body mass index, ND = not determined, DM = diabetes mellitus, CRP = C-reactive protein, CVD = cardiovascular disease, CHD = coronary heart disease, MI = myocardial infarction, PAE = pulmonary artery embolism, PAOD = peripheral arterial occlusive disease, ACM = arteria cerebri media infarction, NSTEMI = non-ST-elevation myocardial infarction, TIA = transient ischemic attack.

^aNo tissue for immunohistochemistry.

^bExsmoker for 10 years.

^cNormal cholesterol levels but increased triglyceride levels.