TABLE 1.
GIV expression as determined by cytosolic and nuclear staining (GIV-positive) of tumor epithelium correlates with tumor aggressiveness
Tumors were scored as either negative or positive for GIV staining as described under “Experimental Procedures.” The p value was determined by χ2 test. LN, lymph node; pos, positive; neg, negative.
| Histologic type | n | GIV-pos | GIV-neg | Percent GIV-pos | χ2 value | p value |
|---|---|---|---|---|---|---|
| Carcinoma in situ | 15 | 4 | 11 | 26.67 | 6.581 | 0.037 |
| Invasive ductal carcinoma without LN metastasis | 15 | 7 | 8 | 53.33 | ||
| Invasive ductal carcinoma with LN metastasis | 15 | 11 | 4 | 73.33 |