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. 2012 Oct 19;287(50):42001–42008. doi: 10.1074/jbc.M112.421883

FIGURE 2.

FIGURE 2.

SMEI-associated mutations exhibit reduced whole-cell current. A, representative whole-cell current from cells stably expressing WT-NaV1.1 (top), R1648C (middle), or G1674R (bottom). B, current-voltage relationship of WT (filled circles), R1648C (open circles), and G1674R (filled triangles). All data are expressed as mean ± S.E. for 6–10 replicates. pF, picofarads.