FIGURE 6.

Effects of intragastric alcohol feeding on mitochondrial morphology in hepatocytes in vivo. A, electron microscopy image of hepatocytes from intragastric or oral alcohol-fed mice and their respective controls. B, assessment of mitochondrial major and minor axes following intragastric alcohol feeding (2 weeks). Major and minor mitochondrial axes were measured using the ImageJ program as described under “Experimental Procedures.” The reference lines on the graph represent the averages of major and minor axes for control mitochondria. n = 4 mice/group. Results are mean ± S.D.; *, p < 0.05 versus control.