FIGURE 7.

Intragastric alcohol feeding increases hepatocyte size and the number of mitochondria in the liver. A, H&E staining of liver from intragastric alcohol (2 weeks) and control mice. B, changes in hepatocyte area with alcohol feeding. Solid bars, control; empty bars, alcohol treatment. Hepatocyte area was measured using ImageJ as described under “Experimental Procedures.” C, mitochondria yield, protein levels/g of liver (wet weight). n = 4–8 mice/group. Results are mean ± S.D. (error bars); *, p < 0.05 versus control.