TABLE 1.
Oral alcohol rats | Oral alcohol mice | Intragastric mice | |
---|---|---|---|
Final body weight (g) | |||
Control | 426 ± 4 | 32.0 ± 3.7 | 22.5 ± 0.55 |
Alcohol | 375 ± 40 | 30.2 ± 1.3 | 21.5 ± 0.35 |
Liver weight (g) | |||
Control | 13.0 ± 1.6 | 1.61 ± 0.29 | 1.20 ± 0.15 |
Alcohol | 14.1 ± 1.1 | 1.74 ± 0.08 | 1.88 ± 0.12a |
Liver/body weight (%) | |||
Control | 3.06 ± 0.36 | 5.01 ± 0.38 | 5.33 ± 0.58 |
Alcohol | 3.78 ± 0.32a | 5.78 ± 0.20a | 8.75 ± 0.52a |
ALT (units/liter) | |||
Control | 30.0 ± 11.5 | 56.7 ± 10.0 | 17.9 ± 4.2 |
Alcohol | 47.5 ± 6.19a | 70.5 ± 21.6 | 223 ± 108a |
a p < 0.05 versus control.