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Effect of 1,25(OH)2D3 supplementation on MCP-1 and adiponectin secretion in 3T3L1 adipocytes exposed to CG or HG either alone or in the presence of PAG or in CSE-siRNA transfection. A, MCP-1. B, adiponectin. C and D, effect of PAG on MCP-1 (C) and adiponectin levels (D). E and F, adiponectin (E) and MCP-1 (F) levels in CSE-siRNA-transfected cells treated with 1,25(OH)2D3 for 2 h followed by CG (7 mm) or HG (25 mm) exposure for the next 20 h. Values are mean ± S.E. (error bars; n = 3).
