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. 2012 Nov 8;2(11):1078–1091. doi: 10.7150/thno.4240

FIGURE 8.

FIGURE 8

Effect of varying DNA dose on the efficiency of in vivo UMGD using cationic or neutral MBs. Overall, gene delivery increased with increased DNA dose with maximum observed at the highest DNA dose of 50 µg. However, the degree of enhancement in UMGD efficiency with using cationic MBs over neutral MBs (C:N) was most prominent at the lowest DNA dose. Bars are means of the maximum radiance at individual peak time points ± standard deviations (in photons/sec/cm2/sr, n=6 per group). * P < 0.05 comparing cationic and neutral MB groups.