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Specific mutations introduced to the epothilone binding pocket of yeast β-tubulin Tub2.
| Tubulin form | Specific mutations |
|---|---|
| Tub2-BBBBB | A19K, T23V, G26D, N227H, Y270F, C-term His6 |
| Tub2-BBBBY | A19K, T23V, G26D, N227H, C-term His6 |
| Tub2-BBBYB | A19K, T23V, G26D, Y270F, C-term His6 |
| Tub2-BBYBB | A19K, T23V, N227H, Y270F, C-term His6 |
| Tub2-BYBBB | A19K, G26D, N227H, Y270F, C-term His6 |
| Tub2-YBBBB | T23V, G26D, N227H, Y270F, C-term His6 |
| Tub2-YYYYY | C-term His6 |
