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. Author manuscript; available in PMC: 2012 Dec 7.
Published in final edited form as: Angew Chem Int Ed Engl. 2010;49(1):34–44. doi: 10.1002/anie.200904491

Scheme 15.

Scheme 15

Natural product synthesis often underlines significant deficiencies in catalyst development, as indicated by an inefficient cross-metathesis reaction in an enantioselective synthesis of elenic acid.