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. Author manuscript; available in PMC: 2012 Dec 7.
Published in final edited form as: Angew Chem Int Ed Engl. 2010;49(1):34–44. doi: 10.1002/anie.200904491

Scheme 8.

Scheme 8

Enantioselective synthesis of the lactone fragment of HIV-protease inhibitor tipranivir through a Mo-catalyzed ring-opening/ring-closing metathesis (RORCM) reaction. Ar = 2,4,6-(iPr)3C6H2