Skip to main content
. Author manuscript; available in PMC: 2012 Dec 7.
Published in final edited form as: ChemMedChem. 2010 Sep 3;5(9):1594–1608. doi: 10.1002/cmdc.201000175

Figure 3.

Figure 3

Pairwise alignment of rat and human Urotensin II receptor (GPCR14). Each transmembrane (TM) helix predicted by TMPredict program is shown with grey shading. Highly conserved residues in Family A receptors are displayed in boxes with Ballesteros numbers. The residues in bold face are important amino acids for UT-II binding. Length= 389 amino acids, Score= 489 bits (1125), Expect=1e-137, Method: Composition-based stats. Identities= 266/328 (74% in whole sequence, 89% in TM helix). Positives= 290/328 (88%), Gaps= 2/328 (0%).