Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthesis of the Sulfone Coupling Partner
| Entry | Conditions | Result |
|---|---|---|
| 1 |
 TfOH (50 mol %), CH2Cl2 |
Decomposition |
| 2 |
 TfOH (5 mol %), CH2Cl2-hexane |
Decomposition |
| 3 |
 Cu(OTf)2, PhMe |
No Reaction |
| 4 |
 BF3·OEt2 |
Decomposition |
| 5 | Allyl bromide, Ag2O, CaSO4, PhH | No Reaction |
| 6 | Et2Zn, Pd(OAc)2, PPh3, allyl acetate, THF | 61% of 39 |
