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. Author manuscript; available in PMC: 2012 Dec 7.
Published in final edited form as: Chemistry. 2010 Aug 16;16(31):9555–9562. doi: 10.1002/chem.201001164

Table 2.

Effect of Silane on Ketone Reductions

graphic file with name nihms-379112-f0012.jpg
Entry Silane Temperature Yield (%) ee (%)
1 Me2PhSiH rt 95 89
2 Et3SiH rt 60 85
3 Ph2MeSiH rt 23 82
4 Ph2SiH2 rt 43 72
5 iPr3SiH rt nr n/a
6 t-BuMe2SiH rt nr n/a
7 Me2PhSiH 0 °C nr n/a
8 Me2PhSiH 60 °C 71 76