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. Author manuscript; available in PMC: 2013 Sep 3.
Published in final edited form as: Angew Chem Int Ed Engl. 2012 Aug 9;51(36):9075–9077. doi: 10.1002/anie.201203708

Figure 2.

Figure 2

Combination of YES and OR gates for the detection and mutation analysis of Mtb DNA. All OR gate, YES gate, UMB1, and UMB2 oligonucleotides were mixed together in the absence or presence of each separate mutant or wildtype analytes. Fluorescence at 580 nm for UMB1 (grey) or 517 nm for UMB2 (black) was recorded after a 15 minute incubation at room temperature. The data is an average of three independent experiments, presented as the ratio of signal to background (S/B). S/B was calculated as a ration of fluorescence in the presence of analyzed sequence to that in the absence.