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. Author manuscript; available in PMC: 2013 Oct 15.
Published in final edited form as: Angew Chem Int Ed Engl. 2012 Sep 24;51(42):10588–10591. doi: 10.1002/anie.201204633

Chart 1.

Chart 1

Three-component indole products and yields. Conditions: 1 mmol o-bromoiodoarene, 1 mmol primary amine, 2 mmol ketone/aldehyde, 2 mol% Pd2dba3, 5 mol% DPPF, 2.2 mmol Cs2CO3, 10 mmol MgSO4, toluene (0.5 M), 130 °C. Yields of isolated product after purification by column chromatography.