Table 1.
Patient Characteristics for the Derivation and Validation Cohorts
| Derivation Cohort (n= 28,629) | Validation Cohort (n= 14,328) | |
|---|---|---|
| DEMOGRAPHICS | ||
| Age | ||
| Mean (SD) | 66.0 (15.2) | 66.2 (15.4) |
| Median (IQR) | 68.0 (56.0, 78.0) | 68.0 (56.0, 78.0) |
| Male Sex, % | 16,046 (56.0) | 8081 (56.4) |
| Black Race, % | 5531 (19.3) | 2813 (19.6) |
| PRE-EXISTING CONDITIONS, % | ||
| CPC Score Prior to Arrest | ||
| 1 | 13404 (52.8) | 6745 (52.9) |
| 2 | 7346 (28.9) | 3704 (29.0) |
| 3 | 3136 (12.4) | 1585 (12.4) |
| 4 or 5 | 1498 (5.9) | 725 (5.7) |
| Missing | 3245 (11.3) | 1569 (11.0) |
| Respiratory Insufficiency | 12739 (44.5) | 6380 (44.5) |
| Renal Insufficiency | 10625 (37.1) | 5319 (37.1) |
| Arrhythmia | 10601 (37.0) | 5348 (37.3) |
| Diabetes Mellitus | 9606 (33.6) | 4892 (34.1) |
| Hypotension | 8172 (28.5) | 4033 (28.1) |
| Heart failure prior to admission | 6792 (23.7) | 3387 (23.6) |
| Heart failure this admission | 6039 (21.1) | 2983 (20.8) |
| Myocardial Infarction prior to admission | 5250 (18.3) | 2712 (18.9) |
| Myocardial Infarction this admission | 5399 (18.9) | 2668 (18.6) |
| Metabolic or Electrolyte Abnormality | 5351 (18.7) | 2708 (18.9) |
| Sepsis | 5087 (17.8) | 2552 (17.8) |
| Pneumonia | 4408 (15.4) | 2110 (14.7) |
| Metastatic or Hematologic Malignancy | 3444 (12.0) | 1721 (12.0) |
| Baseline Depression in CNS Function | 3810 (13.3) | 1867 (13.0) |
| Hepatic Insufficiency | 2489 (8.7) | 1221 (8.5) |
| Acute CNS non-Stroke event | 2388 (8.3) | 1172 (8.2) |
| Acute Stroke | 1212 (4.2) | 622 (4.3) |
| Major Trauma | 1002 (3.5%) | 486 (3.4%) |
Abbreviations: CNS, central nervous system; CPC, Cerebral Performance Score; IQR, inter-quartile range; SD, standard deviation.