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. 2012 May 23;32(21):7316–7324. doi: 10.1523/JNEUROSCI.4284-11.2012

Figure 3.

Figure 3.

Correlations between caudate D2/D3 receptor availability (BPND) and fMRI contrast of Successful Stop versus Go (n = 18). Participants with greater caudate receptor D2/D3 receptor availability had greater activation in frontostriatal brain regions. Image shows Z-statistic map thresholded at Z > 1.96 (whole-brain, cluster-corrected threshold of p < 0.05) overlaid on the mean, spatially normalized anatomical image. A, C, D, Bilateral caudate (A), right inferior frontal cortex/lateral occipital cortex (C, D), and rostral anterior cingulate/superior frontal (medial portion) (D) regions of activation (see Table 4 for full list of regions). Images are presented in radiological orientation (right = left). MNI coordinates: transverse slice, Z = 4 (A); sagittal slice, X = 50 (C); and coronal slice, Y = 34 (D). R, Right. Color bar indicates Z-statistic range. B, Scatterplot shows relationship between dopamine D2/D3 receptor availability and Successful Stop versus Go parameter estimates in anatomically defined caudate VOI (r = 0.82, p = 0.00002; without outlier: r = 0.70, p = 0.002). A weighted average of left and right caudate parameter estimates was used because the two were highly correlated (r = 0.82, p < 0.0001).