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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Integr Biol (Camb). 2012 Dec;4(12):10.1039/c2ib20197f. doi: 10.1039/c2ib20197f

Figure 4. A priori predictions of differentiated morphologies.

Figure 4

A) A compendium of time-dependent kinase signals of patients 8–14 (group II) used for a priori prediction is shown. B) The trained models for macrophages and osteoclasts generated with Group I data were used to predict cell diameter and number of nuclei from Group II kinase data. The model was effective in predicting cell diameter, with 90% predictability for macrophages and 91% predictability for osteoclasts, but only 71% for osteoclast nuclei. With only one nucleus, no variation can be predicted for macrophage. C) Experimental/observed quantification of mean diameter and average number of nuclei per patient (n=7).