Distal Meiotic Events Are in Phase with the Chromatin Cycles of Expansion and Contraction.
During prophase I, nuclei expand at transitional stages and then contract.
(A) Immunolocalization of meiotic proteins ASY1 (red) and ZYP1 (green) in conjunction with a BrdU time course (see Supplemental Figure 5 online) reveals that initial distal meiotic events are synchronized with nuclei expansion periods, whereas the interstitial events occur during periods of nuclei contraction. Bar = 10 µM.
(B) The immunolocalization data are represented, highlighting the difference in loading of meiotic proteins to distal and interstitial chromosomal regions. Data are the mean ± se.