Table 2.  .

Change in Serum Thiobarbituric Acid Reactive Substances, Triglycerides, Free Fatty Acids, Cholesterol, and Angiotensin Converting Enzyme Activity and Corneal Sensitivity, Tear Production and Cornea Thickness in Streptozotocin-Induced Diabetic Rats

Determination	Control (9)	Diabetic (10)	Diabetic + Ilepatril (10)
Thiobarbituric acid reactive substances, μg/mL	0.78 ± 0.04	0.94 ± 0.04*	0.92 ± 0.06
Triglycerides, mg/dL	14 ± 1	130 ± 16*	52 ± 7+
Free fatty acids, mmol/L	0.06 ± 0.01	0.42 ± 0.06*	0.46 ± 0.08*
Cholesterol, mg/mL	1.2 ± 0.1	4.3 ± 0.5*	1.7 ± 0.2+
ACE activity, mU/mL	34 ± 2	55 ± 6*	17 ± 2*,+
Corneal sensitivity, cm	5.97 ± 0.03	5.77 ± 0.07*	6.00 ± 0.00+
Tear production, fiber length, mm	22.3 ± 0.7	15.2 ± 0.8*	17.5 ± 0.6*
Cornea thickness, μm	137 ± 10	126 ± 6	121 ± 6

Data are presented as the mean ± SEM. One unit of angiotensin converting enzyme activity is defined as the amount of enzyme required to release 1 μmol of hippuric acid per minute and per liter of serum at 37°C. *P < 0.05 compared to control, +P < 0.05, compared to diabetic. Parentheses indicate the number of experimental animals.