Adipocyte AGT deficiency had no significant effect on HF-induced elevations in plasma AGT concentrations, but ablated HF-induced elevations in plasma AngII concentrations. A, Plasma AGT concentrations in LF and HF-fed Agtfl/fl and AgtaP2 mice. B, Plasma AngII concentrations in LF and HF-fed Agtfl/fl and AgtaP2 mice. Data are mean ± SEM from n = 7-8 mice/group (LF) and n = 11-14 mice/group (HF). *, P<0.05 compared to LF within genotype. **, P<0.05 compared to Agtfl/fl within diet group.