Table 1.
Patient characteristics
|
Variables |
MM COPD |
ZZ COPD |
|---|---|---|
| N = 3 | N = 3 | |
| |
Mean ± SD |
|
|
A. Transplanted lung tissue used for Affymetrix analysis | ||
| Age (years) |
57 ± 4.8 |
62 ± 2.3 |
| Gender (male/female) |
3/0 |
2/1 |
| Ex-smoker |
3 |
3 |
| Gold stage |
IV |
IV |
| Mean pulmonary art. pressure (mmHg) |
25 ±5.1 |
32 ±12 |
| Cardiac Index () |
3.1 ± 0.3 |
3.0 ± 0.1 |
| GOT (ref < 35U/L) |
32 ± 21.1 |
28 ± 5.0 |
| GPT (ref <45U/L) |
25 ± 16.2 |
29 ± 8.0 |
| Inhaled steroid therapy |
3 |
3 |
| Augmentation therapy with AAT |
0 |
0 |
|
B. Transplanted lung tissue used for RT-PCR analysis | ||
| Age (years) |
53.7 ± 2.7 |
48.3 ± 1.3 |
| Gender (male/female) |
3/0 |
3/0 |
| Ex-smoker |
3 |
3 |
| Gold stage |
IV |
IV |
| Mean pulmonary art. pressure (mmHg) |
n.d. |
28 ± 2.8 |
| Cardiac Index () |
n.d. |
n.d. |
| GOT (ref < 35U/L) |
28 ±6.2 |
28.3 ± 3.4 |
| GPT (ref <45U/L) |
36.7 ± 10.2 |
33.3 ± 9.0 |
| Inhaled steroid therapy |
2 |
3 |
| Augmentation therapy with AAT | 0 | 0 |