Table 3.

Costs and increments in the 6-month period preceding follow-up of the Internet-based therapy (IT) and Internet-based self-help (IS) groups^a.

Cost type		IT		IS		Bootstrapped difference
		Mean	SD	Mean	SD	Median	95% CIb
Intervention costs
	Therapist labor	241	236	0	0	240	187–296
	Software development	23	0	5	0	18	18–18
	Software/hardware service	15	0	2	0	12	12–12
	Software overhead	4	0	4	0	0	0–0
	Total intervention costs	283	236	12	0	271	217–327
Participant time investment costs		95	103	22	37	72	48–99
Productivity costs
	Work absenteeism	1114	5704	536	3800	555	–967 to 2234
	Work presenteeism	217	847	350	1637	–119	–609 to 256
	Total productivity costs	1331	5774	886	4215	417	–1215 to 2208
Societal costs
	Additional societal costsc	301	1305	200	953	94	–275 to 499
	Total societal costs	2010	7141	1120	5167	845	–1157 to 3048
Treatment response (proportion)		0.53		0.29		0.24	0.07–0.38
EQ-5Dd score		0.89	0.20	0.78	0.34	0.12	0.05–0.18
ICERe treatment response						3683	–5703 to 20,366
ICER QALYf						14,710	–18,337 to 71,664

^a All costs have been rounded for presentation in this table, and may therefore not add up exactly.

^b Confidence interval.

^c An estimation of real costs, based on Rehm et al [2], and includes additional health care resource costs and law-enforcement costs.

^d 5-dimensional EuroQol instrument, score calculated using the measurement and valuation of health (MVH-A1) algorithm from Dolan [29].

^e Incremental cost effectiveness ratio.

^f Quality-adjusted life-year.