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. 2012 Aug 28;5:461. doi: 10.1186/1756-0500-5-461

Table 2.

Genotype frequencies of the NR1H4 variants in the study population and the genotype association analysis

SNP rs3863377(G→ A)
 
 WT [GG]
 Het [GA]
 Hom [AA] (%)
 P
 P’
 OR
 CI
 χ2
non-IBD
 506 (94.4)
 28 (5.2)
 2 (0.4)
  
  
  
  
 0.14
IBD
 438 (97.8)
 10 (2.2)
 0
 0.009** †
 0.022*
 0.39
 0.19-0.80
 0.01
CD
 271 (97.8)
 6 (2.2)
 0
 0.030* †
 0.031*
 0.37
 0.15-0.191
 0.01
UC
 167 (97.7)
 4 (2.3)
 0
 0.100 †
 0.066
 0.40
 0.14-1.16
 0.01
SNP rs56163822(−1G → T)
 
 WT [GG]
 Het [GT]
 Horn [TT] (%)
 P
 P’
 OR
 CI
 χ2
non-IBD
 560 (96.6)
 20 (3.4)
 0
  
  
  
  
 0.04
IBD
 505 (93.9)
 33 (6.1)
 1 (0.09)
 0.035*
 0.451
 1.83
 1.04-3.23
 0.00
CD
 319 (94.4)
 19 (5.6)
 1 (0.09)
 0.115
 0.846
 1.67
 0.88-3. 17
 0.00
UC
 186 (93.0)
 14 (7.0)
 0
 0.034*
 0.154
 2.11
 1.04-4.26
 0.13
SNP rs7138843(A → T)
 
 WT [AA]
 Het [AT]
 Horn [TT] (%)
 P
 P’
 OR
 CI
 χ2
non-IBD
 495 (96.7)
 17 (3.3)
 0
  
  
  
  
 0.03
IBD
 417 (95.2)
 21 (4.8)
 0
 0.248
 0.772
 147
 0.76-2.82
 0.06
CD
 261 (96.0)
 11 (4.0)
 0
 0.369 †
 0.612
 1.23
 0.57-2.66
 0.04
UC
 156 (94.0)
 10 (6.0)
 0
 0.097 †
 0.981
 1.87
 0.84-4.16
 0.10
SNP rs10860603(G → A)
 
 WT [GG]
 Het [GA]
 Horn [AA] (%)
 P
 P’
 OR
 CI
 χ2
non-IBD
 424 (72.8)
 143 (24.6)
 15 (2.6)
  
  
  
  
 049
IBD
 407 (75.8)
 121 (22.5)
 9 (1.7)
 0.261
 0.384
 0.86
 0.66-1.12
 0.00
CD
 254 (75.4)
 76 (22.5)
 7 (2.1)
 0.403
 0.611
 0.88
 0.65-1.19
 0.22
tiC
 153 (76.5)
 45 (22.5)
 2 (1.0)
 0.312
 0.521
 0.82
 0.57-1.19
 0.43
SNP rs35724(G→ C)
 
 WT [GG]
 Het [GC]
 Horn [CC] (%)
 P
 P’
 OR
 CI
 χ2
non-IBD
 217 (37.3)
 264 (454)
 101 (17.3)
  
  
  
  
 1.78
IBD
 177 (32.9)
 251 (46.7
 110 (20.4)
 0.125
 0.209
 1.213
 0.95-1.55
 1.47
CD
 111 (32.8)
 155 (45.9)
 72 (21.3)
 0.175
 0.279
 1.216
 0.92-1.61
 1.68
UC 66 (33.0) 96 (48.0) 38 (19.0) 0.277 0.233 1.207 0.86-1.69 0.09