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. 2012 Jul 17;12:58. doi: 10.1186/1471-2377-12-58

Table 2.

Relationship between selected parameters and cTNI elevation in patients with epileptic seizure

  Total cohort (n = 741) cTNI elevation(n = 50) cTNI negative(n = 691) P* P
Age (years); median (range)
47.8 (17.5 –89.9)
61.9 (21.6 – 88.1)
46.8 (17.5 – 89.9)
<0.001
0.07
Gender
 
 
 
0.77
 
 Female
303 (40.9%)
19 (38%)
284 (41.1%)
 
 
 Male
438 (59.1%)
31 (62%)
407 (58.9%)
 
 
CK elevated on admission
303 (40.9%)
27(54%)
276 (39.9%)
<0.001
0.002
Further subsequent CK increase after admission
187 (25.2%)
24 (48%)
163 (23.6%)
<0.001
 
Cr elevated on admission
85 (11.5%)
16 (32%)
69 (10%)
0.05
0.14
eGFR (ml/min/1,73 m2 body surface), median (range)
76.9 (43.8 – 162.8)
76.1 (45.9 – 162.8)
76.9 (43.8 – 159.3)
0.40
 
Hypertension
155 (20.9%)
16 (32%)
139 (20.1%)
0.07
 
Hypercholesterolemia
117 (15.8%)
12 (24%)
105 (15.2%)
0.11
 
Diabetes
75 (10.1%)
9 (12%)
66 (9.6%)
0.08
 
Intake of Beta-blocker
92(12.4%)
15(30%)
77 (11.1%)
<0.001
0.63
Known CAD
96 (13%)
18 (36%)
78 (11.3%)
<0.001
0.56
Vascular risk profile
193 (33.9%)
32(64%)
161(23.3%)
<0.001
0.001
Regular alcohol consumption
222 (30%)
17 (34%)
205 (29.7%)
0.52
 
Known epilepsy
251 (33.9%)
25 (50%)
226 (32.7%)
0.02
0.18
Symptomatic epilepsy
249 (33.6%)
23 (46%)
226 (32.7%)
0.06
0.52
Intake anticonvulsants 231 (31.2%) 23 (46%) 208 (30.1%) 0.02 0.34

*P value calculated in the univariate analysis.

P value calculated in the logistical regression.

CK refers to serum creatine kinase.

Cr refers to serum creatinine.

CK cut-off level > 140U/l in females and > 174 U/l in males.

Cr cut-off level > 1.2 mg/dl in females and > 1.3 mg/dl in males.

eGFR refers to estimated glomerular filtration rate.