Table 2.
Relationship between selected parameters and cTNI elevation in patients with epileptic seizure
| Total cohort (n = 741) | cTNI elevation(n = 50) | cTNI negative(n = 691) | P* | P† | |
|---|---|---|---|---|---|
| Age (years); median (range) |
47.8 (17.5 –89.9) |
61.9 (21.6 – 88.1) |
46.8 (17.5 – 89.9) |
<0.001 |
0.07 |
| Gender |
|
|
|
0.77 |
|
| Female |
303 (40.9%) |
19 (38%) |
284 (41.1%) |
|
|
| Male |
438 (59.1%) |
31 (62%) |
407 (58.9%) |
|
|
| CK elevated on admission |
303 (40.9%) |
27(54%) |
276 (39.9%) |
<0.001 |
0.002 |
| Further subsequent CK increase after admission |
187 (25.2%) |
24 (48%) |
163 (23.6%) |
<0.001 |
|
| Cr elevated on admission |
85 (11.5%) |
16 (32%) |
69 (10%) |
0.05 |
0.14 |
| eGFR (ml/min/1,73 m2 body surface), median (range) |
76.9 (43.8 – 162.8) |
76.1 (45.9 – 162.8) |
76.9 (43.8 – 159.3) |
0.40 |
|
| Hypertension |
155 (20.9%) |
16 (32%) |
139 (20.1%) |
0.07 |
|
| Hypercholesterolemia |
117 (15.8%) |
12 (24%) |
105 (15.2%) |
0.11 |
|
| Diabetes |
75 (10.1%) |
9 (12%) |
66 (9.6%) |
0.08 |
|
| Intake of Beta-blocker |
92(12.4%) |
15(30%) |
77 (11.1%) |
<0.001 |
0.63 |
| Known CAD |
96 (13%) |
18 (36%) |
78 (11.3%) |
<0.001 |
0.56 |
| Vascular risk profile |
193 (33.9%) |
32(64%) |
161(23.3%) |
<0.001 |
0.001 |
| Regular alcohol consumption |
222 (30%) |
17 (34%) |
205 (29.7%) |
0.52 |
|
| Known epilepsy |
251 (33.9%) |
25 (50%) |
226 (32.7%) |
0.02 |
0.18 |
| Symptomatic epilepsy |
249 (33.6%) |
23 (46%) |
226 (32.7%) |
0.06 |
0.52 |
| Intake anticonvulsants | 231 (31.2%) | 23 (46%) | 208 (30.1%) | 0.02 | 0.34 |
*P value calculated in the univariate analysis.
†P value calculated in the logistical regression.
CK refers to serum creatine kinase.
Cr refers to serum creatinine.
CK cut-off level > 140U/l in females and > 174 U/l in males.
Cr cut-off level > 1.2 mg/dl in females and > 1.3 mg/dl in males.
eGFR refers to estimated glomerular filtration rate.