Table 1.
Demographic information
| PSP(n = 19) | PD(n = 20) | HOA(n = 20) | ||
|---|---|---|---|---|
|
Age, yrs |
69.1 (8.7) |
68.3 (7.9) |
71.8 (4.1) |
n/s |
|
Male, n(%) |
16 (84) |
16 (80) |
7 (35) |
P = 0.001 |
|
Height, cm |
170.6 (8.2) |
171.8 (8.0) |
166.6 (6.3) |
n/s |
|
Weight, kg |
80.5 (13.5) |
78.3 (10.2) |
68.4 (11.5) |
F2,56 = 5.9, P = 0.01 |
|
Symptom duration, yrs |
4.3 (2.7) |
6.6 (5.8) |
- |
n/s |
|
Disease severity |
41.7 (17.2) |
14.4 (16.7) |
- |
- |
|
Normalized speed |
1.03 (0.27) |
1.28 (0.22) |
1.54 (0.16) |
F2,56 = 25.8, P < 0.001 |
|
Normalized stride length |
1.2 (0.2) |
1.4 (0.2) |
1.6 (0.1) |
F2,56 = 25.6, P < 0.001 |
|
Cadence (steps/min) |
103.6 (9.3) |
109.7 (6.9) |
113.4 (7.0) |
F2,56 = 7.9, P = 0.001 |
|
Cadence (steps/min)* |
119.8 (15.4) |
108.9 (18.9) |
92.7 (9.5) |
F2,56= 15.9, P <0.001 |
|
DS (%)* |
31.1 (4.6) |
27.9 (3.0) |
25.6 (2.7) |
F2,56 = 12.2, P < 0.001 |
|
Step width (cm)* |
11.4 (4.2) |
9.0 (2.9) |
8.5 (2.9) |
F2,56 = 4.0, P = 0.02 |
|
Stance time variability (sec)* |
0.024 (0.009) |
0.018 (0.008) |
0.025 (0.013) |
n/s |
| Stride length variability (cm)* | 3.2 (1.7) | 2.4 (1.2) | 2.8 (1.6) | n/s |
Mean (standard deviation, SD) for each group. Disease severity was measured using PSP Rating Scale for PSP participants (0=no symptoms – 100) and Unified Parkinson’s Disease Rating Scale – motor subsection (UPDRS III) for PD participants (0=no symptoms – 56). Mean (SD) normalized speed, normalized stride length and cadence for preferred speed walks. Mean (SD) of other gait parameters for the walk with normalized stride length closest to 1.4.
* Determined from walk with normalized stride length closest to 1.4. PSP progressive supranuclear palsy, PD Parkinson’s disease, HOA healthy older adult, DS double support percentage of gait cycle, n/s not statistically significant.