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. 2012 Oct 30;13:33. doi: 10.1186/1471-2199-13-33

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Copyright ©2012 Killen et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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RecG expression reduces SCE in a French-Canadian BLM-line. 3A: Normalized sister chromatid exchange frequencies. “BLM- FC”: EBV-immortalized lymphocytes homozygous for an inactivating (S595X) mutation. “BLM- FC: RecG fuse”: the same cells expressing low levels of the RecG-EGFP fusion protein. 3B: Western blot showing relative protein levels. Blue oval: RecG-EGFP fusion protein. “BLM- FC: RecG fuse”: protein extract from French-Canadian BLM- cells stably expressing low levels of the RecG-EGFP fusion protein. “BLM- FC”: protein from French-Canadian BLM- cells lacking a RecG transgene. See also Table 1 for EGFP quantitation by flow cytometry.