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. 2012 Dec 7;7(12):e51303. doi: 10.1371/journal.pone.0051303

Table 2. Immunhistochemical analysis of the healing of TM perforations in WT, tPA−/− and uPA−/− mice.

Number of days after perforation
Genotype Day 9 Day 12 Day 15
WT 6/10 (60%) 9/10 (90%) 10/10 (100%)
tPA−/− 11/18 (61%) 9/10 (90%) 10/10 (100%)
uPA−/− 1/18 (6%) 6/10 (60%) 10/10 (100%)
P value 0.000912*** 0.153355 N/A

The data are shown as the number of closed TM perforations with a continuous keratin layer in relation to the total number of TM perforations examined. The healing rate was calculated and is shown in brackets. *** P<0.001.