Table 3.
Structural predictions for Caenorhabditis LBDs by sequence threading
| LBD | Best structural match | PDB ID | P |
|---|---|---|---|
| CbNHR-67 |
H. sapiens NR2C2 TR4 LBD |
3p0u |
1 x 10-6 |
| CeNHR-67 |
H. sapiens NR2C2 TR4 LBD |
3p0u |
9 x 10-7 |
| CbFAX-1 |
H. sapiens NR2F2 COUP LBD |
3cjw |
0.024 |
| CeFAX-1 |
H. sapiens NR2F2 COUP LBD |
3cjw |
0.003 |
| CeNHR-111 |
H. sapiens NR2F2 COUP LBD |
3cjw |
1 x 10-5 |
| CbNHR-239 |
No significant matches. |
- |
> 0.10 |
| CeNHR-239 | No significant matches. | - | > 0.05 |
Probability values (P) and top match for Caenorhabditis LBDs based on PsiPred and pGenThreader [52,53]. Additional significant matches to known NR LBD structures were obtained for each protein, however the significance of matches for both FAX-1 LBDs was low. Species abbreviations are given in Figure 1.