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. 2012 Dec 7;7(12):e51633. doi: 10.1371/journal.pone.0051633

Figure 3. Immunity elicited by Env and CD40Lm expressing m8 Δ prime followed by recombinant SeV boost.

Figure 3

(A) Schematic schedules of m8Δ prime/rSeV-Env boost vaccination protocol. Mice were primed with various vaccinia viruses followed by Env expressing SeV boost. Group G: primed with m8Δ-Env plus m8Δ-p7.5hCD40Lm; group H: m8Δ-Env plus m8Δ; group I: m8Δ-Env/hCD40Lm; group J: m8Δ-Env; group K: m8Δ; group L: naive. (B) Comparison of Env peptide-specific CD8+ T cell responses. The percentage of IFN-γ+ expressing cells in gated CD8+ T cell compartment was measured by ICS and FACS analysis. (C) The percentage of IFN-γ+ T cells in gated CD4+ T cell compartment.