Figure 6. There is no change in expression of integrin β1 in Alport glomeruli.

A–C: Fresh frozen kidney sections from 4 week old wild-type (wt) mice, immunolabeled with anti-integrin β1 (A), anti collagen α3α4α5(IV) (B) and overlap of labeling is shown in C (merge). D–F: Representative fluorescence micrographs of wildtype (D) and Alport glomeruli immunolabled with anti-integrin β1. Glomerular fluorescence intensities were averaged for n = 3 mice of each genotype, wild-type (wt, blue) or Alport (red), and there is no statistical difference.