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Ultrastructural feature of the co-cultured spheroids by transmitting electron microscopy (TEM) on day 7 of culture. The spheroids are characterized by tight junctions (Tj) between adjacent cells, distinct nuclei (N), abundant mitochondria (M), peroxisomes (P), rough endoplasmic reticulum (rER), collagen accumulation (Col), glycogen vesicles (Gl), and bile canaliculi (B).
