Table 1. Genotype characteristics of each single nucleotide polymorphism.

Gene	SNP	Function	Allelea	Case (MAF)	Control (MAF)	OR (95% CI)	P-value	HWEb
IL21	rs907715	Intron	A/G	0.420	0.463	0.84 (0.74–0.96)	0.01	0.37
IL21	rs2221903	Intron	G/A	0.115	0.098	1.19 (0.96–1.47)	0.11	0.18
IRF5	rs4728142	Flanking 5' UTR	A/G	0.164	0.119	1.45 (1.20–1.75)	9.79×10−5	0.92
IKZF1	rs4917014	Flanking 5' UTR	G/T	0.267	0.331	0.74 (0.64–0.85)	2.56×10−5	0.39
ETS1	rs6590330	Flanking 3' UTR	A/G	0.407	0.345	1.30 (1.14–1.49)	1.15×10−4	0.26
MiR146a	rs57095329	Promoter	G/A	0.214	0.200	1.09 (0.93–1.28)	0.29	0.62

MAF, minor allele frequency; 95% CI, 95% confidence intervals; HWE, Hardy-Weinberg Equilibrium.

^anor allele/major allele;

^bP-value for HWE.