Table 1. Baseline characteristics of mothers whose children were children enrolled in the trial of quarterly albendazole versus placebo from age 15 months to five years.
Albendazole Placebo | Albendazole | ||
Number of mothers with children randomiseda | 994 | 1002 | |
Age in years, mean ± SD | 23.95±5.38 | 23.76±5.43 | |
Education (4 mv)b | |||
None | 36 (4%) | 33 (3%) | |
Primary | 498 (50%) | 509 (51%) | |
Secondary | 381 (38%) | 362 (36%) | |
Tertiary | 79 (8%) | 94 (9%) | |
Household socioeconomic status (41 mv)c | |||
(low) 1 | 48 (5%) | 67 (7%) | |
2 | 77 (8%) | 88 (9%) | |
3 | 320 (33%) | 289 (30%) | |
4 | 280 (29%) | 281 (29%) | |
5 | 190 (19%) | 203 (21%) | |
(high) 6 | 62 (6%) | 50 (5%) | |
Gravidity | |||
1 | 247 (25%) | 265 (26%) | |
2–4 | 582 (59%) | 571 (57%) | |
≥5 | 165 (17%) | 166 (17%) | |
Trimester at treatment (3 mv) | |||
2 | 512 (52%) | 506 (51%) | |
3 | 482 (48%) | 493 (49%) | |
Maternal history of asthma (1 mv) | 19 (2%) | 22 (2%) | |
Helminth infections | |||
Hookworm (7 mv) | 459 (46%) | 409 (41%) | |
S. mansoni (7 mv) | 189 (19%) | 177 (18%) | |
M. perstans (8 mv) | 222 (22%) | 201 (20%) | |
HIV positive | 109 (11%) | 94 (9%) | |
Malaria parasitaemia (36 mv) | 104 (11%) | 93 (9%) | |
Owns mosquito net (3 mv) | 494 (50%) | 519 (52%) | |
Intermittent preventive treatment for malaria during pregnancy (91 mv) | |||
1 dose | 230 (24%) | 209 (22%) | |
2 doses | 626 (66%) | 654 (68%) | |
≥3 doses | 87(10%) | 99 (10%) | |
Maternal tetanus immunisation during pregnancy | |||
0 doses | 220 (22%) | 231 (23%) | |
1 dose | 600 (60%) | 592 (59%) | |
≥2 doses | 174 (18%) | 179 (18%) | |
Maternal treatment | |||
Albendazole+praziquantel | 244 (24%) | 256 (26%) | |
Albendazole placebo+praziquantel | 247 (25%) | 249 (25%) | |
Albendazole+praziquantel placebo | 247 (25%) | 257 (26%) | |
Double placebo | 256 (26%) | 240 (24%) |
The number of mothers with children randomised is lower than the number of children randomised due to 20 sets of twins.
mv: missing values.
Household socioeconomic status was scored based on building materials of the home, number of rooms and items owned, “1” representing lowest and “6” representing highest status.