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. 2012 Sep 19;303(10):F1460–F1472. doi: 10.1152/ajprenal.00426.2012

Fig. 12.

Fig. 12.

HEK 293 and HK-2 cell Hpx and HO-1 protein levels following a hemin challenge. Incubation of either cell line with hemin failed to increase Hpx protein levels, as assessed in cell protein extracts. Conversely, both cell lines responded to hemin with significant increases in HO-1 protein, confirming that the cells were capable of synthesizing a heme-inducible protein.