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. 2012 Sep 11;303(10):E1234–E1244. doi: 10.1152/ajpendo.00198.2012

Fig. 7.

Fig. 7.

Leucine suppresses pseudokinase tribble 3 (TRB3) expression and improves insulin signaling in the liver. A: Expression of TRB3 in liver was analyzed by WB using an anti-TRB3 antibody (n = 5 per group). *P < 0.05 vs. HFD. B: liver homogenates were immunoprecipitated with anti-TRB3 antibody and then probed with an anti-Akt antibody by WB (n = 5 in each group). *P < 0.05 vs. HFD. C: liver homogenates were subjected to WB analysis to determine expression of total and phospho-Akt (Ser437; n = 5 per group). *P < 0.05 vs. ND; #P < 0.05 vs. ND/Ins; †P < 0.05 vs. HFD/Ins.