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Kinetics of butyrate (10 mM, 1 h) effects on MCT1 function (pCMBS-sensitive [14C]butyrate uptake)
| Control | Butyrate, 10 mM | |
|---|---|---|
| Vmax, nmol/mg protein/5 min | 2.2 ± 0.2 | 4.5 ± 0.4* |
| Km, mM | 3.8 ± 0.1 | 3.8 ± 0.3 |
Values are means ± SE; n = 3. Kinetic parameters were analyzed by regression analysis using GraphPad Prism software. MCT1, monocarboxylate transporter 1; pCMBS, p-chloromercuribenzene sulfonate.
P < 0.05.
