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. 2012 Sep 20;303(10):G1134–G1143. doi: 10.1152/ajpgi.00321.2012

Fig. 4.

Fig. 4.

Proliferative effects of pressure, strain, and the combination of pressure and strain on Caco-2 (A and C) and IEC-6 (B and D) cells grown on collagen I or tissue fibronectin matrix. A and B: pressure, strain, and the combination of pressure and strain significantly enhance proliferation of Caco-2 (A) and IEC-6 (B) cells grown on collagen I (n = 12). C and D: pressure decreases and strain increases proliferation of Caco-2 (C) and IEC-6 (D) cells grown on tissue fibronectin. Proliferation is significantly higher in both cell types after exposure to pressure + strain (n = 12). *P < 0.05.