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Caerulein-induced pancreatitis decreases hydrolase activities in lysosome-enriched pancreatic tissue fractions
| Lysosomal Hydrolase | Activity vs. Saline Control |
|---|---|
| CatB | 0.43 ± 0.07 |
| CatL | 0.27 ± 0.11 |
| Asparaginyl endopeptidase (or legumain) | 0.36 ± 0.10 |
| CatD | 0.49 ± 0.05 |
Values are means ± range from 2 independent experiments. Activity was measured in rat pancreatic tissue fractions obtained as described by Mareninova et al. (65). CatB, CatL, and CatD, cathepsins B, L, and D.
