Fig. 9.

Genes perturbed by OVA exposure are also differentially expressed in lymphoblastoid cell lines from asthmatic patients. Maternal OVA exposure affects genes in BN (n = 36) and Lewis (n = 61) rat strains that are also differentially expressed in lymphoblastoid cell lines of asthmatic vs. nonasthmatic human sibling pairs in Moffatt et al. 2007 (21). The contingency tables show the number of overlapping genes between the rat and human data. The significance of overlap was assessed using the Fisher exact test. The odds ratio represents the fold enrichment or strength of the overlap.