Table 4.

Comparison of mRNA and protein expression of amino acid transporters in response to resistance exercise coupled with essential amino acid ingestion or resistance exercise alone in skeletal muscle of older men.

Study Group	Basal	3h Post RE	6h Post RE
	LAT1/SLC7A5 mRNA, Fold Change
RE+EAA	1.09 ± 0.19	3.92 ± 1.43*	5.88 ± 2.25*
RE	1.33 ± 0.31	4.08 ± 0.82*	4.06 ± 1.40*
	SNAT2/SLC38A2 mRNA, Fold Change
RE+EAA	1.02 ± 0.08	1.74 ± 0.52‡	1.21 ± 0.37
RE	1.01 ± 0.16	1.63 ± 0.35‡	1.08 ± 0.40
	PAT1/SLC36A1 mRNA, Fold Change
RE+EAA	1.02 ± 0.10	1.33 ± 0.32	1.73 ± 0.37
RE	1.29 ± 0.38	1.63 ± 0.14	2.71 ± 0.64*
	CAT1/SLC7A1 mRNA, Fold Change
RE+EAA	1.05 ± 0.14	3.53 ± 0.93‡	5.02 ± 1.20‡
RE	1.27 ± 0.18	3.79 ± 1.15‡	5.37 ± 1.70‡
	CD98/SLC3A2 mRNA, Fold Change
RE+EAA	1.01 ± 0.05	1.18 ± 0.28	1.48 ± 0.25
RE	1.35 ± 0.27	1.50 ± 0.21	2.04 ± 0.33*
	LAT1 Protein, Fold Change
RE+EAA	1.00	1.27 ± 0.20	1.24 ± 0.21
RE	1.00	1.10 ± 0.14	0.90 ± 0.13
	SNAT2 Protein, Fold Change
RE+EAA	1.00	1.20 ± 0.11	0.82 ± 0.19
RE	1.00	1.00 ± 0.01	0.99 ± 0.01

Data are mean±SE. RE+EAA = resistance exercise followed by ingestion of 20 g of essential amino acids 1h following exercise; RE = resistance exercise without EAA ingestion. RE+EAA, n = 6; RE, n = 8 (mRNA) and n = 7 (SNAT2 protein) and n = 6 (LAT1 protein).

^*Significant change from basal (p<0.05);

^‡Significant time effect vs. basal (p<0.05).