Skip to main content
. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Int J Neuropsychopharmacol. 2012 Jul 31;16(4):869–888. doi: 10.1017/S1461145712000715

Fig. 7.

Fig. 7

Monoamine oxidase (MAO)A/B knockout (KO) mice exhibit morphological abnormalities in the cerebellum. (a–c) Representative photographs of Nissl stained cerebellar layers. Cerebellar layers are labelled in yellow and red arrows represent the Purkinje cells. (d–f) MAOA/B KO animals have significantly fewer Purkinje cells than wild-type (WT) and MAOA KO mice. Moreover, MAOA/B KO mice show an increase in the molecular layer (ML) thickness compared to WT mice and in the granule cell layer (GCL) thickness compared to MAOA KO mice. Values are displayed as means±S.E.M. *p<0.05 and ***p<0.001 compared to WT mice. #p<0.05 and ##p<0.01 compared to MAOA KO mice. Cerebellar layers n=5–8. PCL, Purkinje cell layer.