Table 3.

Comparison between first and second MR examinations: weighted mean T1 values of each ROI with manual slice-matching and automated registration

	Patients		Controls
	Manual matching	Registration	Manual matching	Registration
ICC(2,1) (CI)	0.893 (0.813–0.940)	0.902 (0.827–0.945)	0.849 (0.732–0.917)	0.851 (0.736–0.919)
r (CI)	0.892 (0.809–0.940)	0.901 (0.824–0.945)	0.855 (0.742–0.921)	0.858 (0.745–0.923)
slope (CI)	1.030 (0.412–1.649)	1.036 (0.383–1.688)	1.044 (0.589–1.499)	1.065 (0.506–1.624)

ICC(2,1) two-way random intraclass correlation coefficient based on single measures, r Pearson’s correlation coefficient, slope the slope obtained with a total least squares fit, CI 95% confidence interval