Table 5.
Lipoxygenase activity of crude extracts and fractions of 6 plants from the Mascarene Islands
|
Concentrations (μg/mL) |
Lipoxygenase inhibition |
|||||
|---|---|---|---|---|---|---|
| Crude water extract | Crude methanol extract | Dichloromethane | Ethylacetate | n-butanol | Water fraction | |
| 10 |
82.46 ± 10.09* |
79.75 ± 10.07* |
77.88 ± 6.37* |
53.71 ± 4.17* |
27.46 ± 1.77* |
32.80 ± 1.31* |
| |
{97.06 ± 11.67*} |
{98.32 ± 7.64*} |
{81.21 ± 5.24*} |
{63.94 ± 3.13*} |
{74.98 ± 2.23*} |
{67.81 ± 4.47*} |
| |
[53.69 ± 2.36*] |
[38.88 ± 1.09*] |
[52.54 ± 0.95*] |
[53.31 ± 1.26*] |
[17.87 ± 1.01*] |
[48.64 ± 2.07*] |
| |
(13.59 ± 1.01) |
(23.03 ± 0.95*) |
(41.13 ± 1.68*) |
(30.96 ± 1.33*) |
(13.35 ± 0.67) |
(13.11 ± 0.67) |
| |
∫10.39 ± 0.96∫ |
∫9.39 ± 1.01∫ |
∫9.45 ± 0.34∫ |
∫11.69 ± 0.66∫ |
∫12.39 ± 1.03∫ |
∫ 9.68 ± 0.91∫ |
| |
∣1.23 ± 0.02 ∣ |
∣5.62 ± 0.68∣ |
∣0.96 ± 0.02∣ |
∣2.36 ± 0.02∣ |
∣14.96 ± 0.66*∣ |
∣2.85 ± 0.51∣ |
| 5 |
69.37 ± 9.37* |
62.69 ± 6.11* |
58.37 ± 3.64* |
28.67 ± 3.09* |
11.09 ± 0.67 |
19.67 ± 0.99 |
| |
{70.16 ± 5.55* } |
{83.67 ± 4.36*} |
{68.69 ± 2.01*} |
{42.67 ± 3.15*} |
{56.04 ± 2.16*} |
{46.39 ± 3.37*} |
| |
[37.11 ± 1.39*] |
[18.39 ± 2.67*] |
[29.67 ± 0.36*] |
[36.56 ± 0.76*] |
[9.36 ± 0.67] |
[32.05 ± 1.16*] |
| |
(7.51 ± 0.77) |
(16.37 ± 0.88*) |
(28.34 ± 1.09*) |
(14.36 ± 1.45*) |
(7.57 ± 0.84) |
(8.34 ± 0.34) |
| |
∫9.67 ± 0.82∫ |
∫7.64 ± 0.36∫ |
∫6.37 ± 0.22∫ |
∫ 6.37 ± 0.98∫ |
∫7.72 ± 0.23∫ |
∫5.37 ± 0.62∫ |
| |
∣0.96 ± 0.03∣ |
∣2.37 ± 0.11∣ |
∣0.57 ± 0.01∣ |
∣1.09 ± 0.03∣ |
∣ 7.09 ± 0.35∣ |
∣1.06 ± 0.02∣ |
| 2.5 |
56.09 ± 7.67* |
50.37 ± 3.07* |
32.67 ± 1.06* |
20.37 ± 2.01* |
7.19 ± 0.65 |
9.37 ± 0.67 |
| |
{53.37 ± 4.31*} |
{62.37 ± 3.16*} |
{50.37 ± 2.67*} |
{37.65 ± 1.11*} |
{39.67 ± 1.97*} |
{35.67 ± 2.01*} |
| |
[26.09 ± 1.03*] |
[10.09 ± 1.37] |
[13.06 ± 0.26] |
[27.39 ± 1.03*] |
[5.36 ± 0.58] |
[24.31 ± 1.09*] |
| |
(3.36 ± 0.17) |
(8.67 ± 0.36) |
(12.04 ± 1.11) |
(8.34 ± 0.67) |
(5.01 ± 0.11) |
(5.06 ± 0.25) |
| |
∫6.37 ± 0.66∫ |
∫4.09 ± 0.46∫ |
∫4.36 ± 0.07∫ |
∫4.09 ± 0.54 ∫ |
∫4.46 ± 0.33∫ |
∫3.64 ± 0.36∫ |
| |
∣0.67 ± 0.02∣ |
∣1.06 ± 0.02∣ |
∣0.36 ± 0.02∣ |
∣0.67 ± 0.02∣ |
∣4.53 ± 0.54∣ |
∣0.97 ± 0.06∣ |
| 1.25 |
32.37 ± 2.07* |
29.67 ± 2.01* |
28.03 ± 0.45* |
11.09 ± 0.37 |
2.37 ± 0.53 |
4.09 ± 0.36 |
| |
{42.37 ± 2.01*} |
{48.69 ± 2.16*} |
{32.69 ± 1.97*} |
{13.39 ± 0.12} |
{26.67 ± 1.37*} |
{29.67 ± 1.36*} |
| |
[10.09 ± 0.96] |
[6.37 ± 0.65] |
[7.63 ± 0.11] |
[11.03 ± 0.15] |
[3.34 ± 0.27] |
[9.03 ± 0.37] |
| |
(1.55 ± 0.01) |
(5.34 ± 0.11) |
(9.37 ± 0.15) |
(5.34 ± 0.60) |
(2.09 ± 0.03) |
(2.04 ± 0.11) |
| |
∫2.39 ± 0.09∫ |
∫1.96 ± 0.02∫ |
∫2.34 ± 0.03∫ |
∫2.39 ± 0.23∫ |
∫1.07 ± 0.07∫ |
∫1.37 ± 0.01∫ |
| ∣0.29 ± 0.01∣ | ∣0.64 ± 0.01∣ | ∣0.24 ± 0.01∣ | ∣0.47 ± 0.01∣ | ∣2.07 ± 0.16∣ | ∣0.17 ± 0.01∣ | |
Note. Values are means ± SD of three independent experiments. AM {FF}[OT] (MC) ∫EM∫ ∣PS∣. *Values significantly different (p < 0.05) from the control in each group.