Table 4.
Representativeness of the PSC vs non-PSC and the T25FW and non-T25FW cohorts
| Characteristic | PSC | Non-PSC | P-value | T25FW | Non-25FW | P-value |
|---|---|---|---|---|---|---|
| Gender, % |
N = 2169 |
N = 1397 |
0.0384 |
N = 184 |
N = 3382 |
0.8527 |
| Male |
38 |
34 |
|
36 |
37 |
|
| Female |
62 |
66 |
|
64 |
63 |
|
| Employment type, % |
N = 1048 |
N = 593 |
0.0004 |
N = 98 |
N = 1543 |
0.2362 |
| Manual skilled |
25 |
30 |
|
22 |
27 |
|
| Manual unskilled |
15 |
19 |
|
12 |
17 |
|
| Non-Manual |
60 |
51 |
|
66 |
56 |
|
| Time since diagnosis, |
|
|
|
|
|
|
| N |
N = 1941 |
N = 1156 |
0.0330 |
N = 176 |
N = 2921 |
0.6199 |
| Mean years |
6.2 |
5.7 |
|
5.8 |
6.0 |
|
| Mobility problems (PRF-reported), mean |
N = 2124 |
N = 1381 |
|
N = 181 |
N = 3324 |
|
| Paraesis |
0.90 |
0.86 |
0.2499 |
0.90 |
0.88 |
0.5122 |
| Plegia |
0.25 |
0.26 |
0.9536 |
0.25 |
0.25 |
0.9063 |
| Spasticity |
0.59 |
0.48 |
0.0001 |
0.61 |
0.54 |
0.1503 |
| Muscle atrophy |
0.15 |
0.09 |
0.0001 |
0.03 |
0.14 |
0.0085 |
| Spasms/cramps |
0.29 |
0.22 |
0.0001 |
0.30 |
0.26 |
0.2680 |
| Footdrop |
0.15 |
0.08 |
0.0001 |
0.13 |
0.12 |
0.4241 |
| Ataxia |
0.58 |
0.53 |
0.1016 |
0.54 |
0.56 |
0.9508 |
| Dystonia |
0.04 |
0.02 |
0.0091 |
0.04 |
0.03 |
0.4537 |
| Fatigue |
0.84 |
0.77 |
0.0219 |
0.85 |
0.81 |
0.3428 |
| Most recent EDSS score |
|
|
|
|
|
|
| N |
N = 1845 |
N = 1211 |
0.5724 |
N = 151 |
N = 2905 |
0.4510 |
| Mean | 3.24 | 3.20 | 3.1 | 3.2 |