Table 3.
Comparing the learning curve of different studies of CLE in the GI tract.
| Present study | Kuiper et al. Gastrointest Endosc 2012 [5] |
Buchner et al. Gastrointest Endosc 2011 [6] |
Neumann et al. Histol Histopathol 2011 [7] | Gaddam et al. Am J Gastroenterol 2011 [8] | |
|---|---|---|---|---|---|
| Type of confocal laser | pCLE | iCLE | pCLE | pCLE | pCLE |
| Tissue | Stomach (GIM) | Colonic polyp | Colonic polyp | Colon (IBD) | Esophagus (Barrett) |
| Number of reader | 5 | 3 | 11 | 2 | 3 |
| Number of center | 1 | 1 | 3 | 1 | 1 |
| Type of study | Offline study | Offline study | Offline study | Offline study | Offline study |
| Training duration | 1 hr | N/A | 2 hr | N/A | 1 hr |
| Intraobserver agreement (κ) | N/A | Yes (0.68–0.84) | N/A | N/A | N/A |
| Interobserver agreement (κ) | Yes (0.52–0.86) | Yes (0.67–0.73) | N/A | N/A | Yes (0.48–0.68) |
| Conclusion | Easy to learn | Easy to learn | Easy to learn | Easy to learn | Short learning curve |
pCLE: probe-based confocal laser endomicroscope, iCLE: integrated confocal laser endomicroscope, GIM: gastric intestinal metaplasia, IBD: inflammatory bowel disease, and N/A: no data.